Ryan was not alone in the industry. Rath Packing Company began in Dubuque with its founder, George John RATH. A number of pork packing companies established themselves early in the industry. The J. H. STROBEL AND SONS PACKING COMPANY was founded in 1857 as a wholesale and retail meat-dealing firm. In 1891 the Dubuque Butcher's Association and the Dubuque Packing and Provision Company merged to form the Dubuque Packing Company. Armour and Company opened a cold storage house at Third and Iowa STREETS in November 1893. H. S. Hetherington opened a plant on 4th and White in November 1894. The Trenkle sausage factory, established in 1896, was producing four thousand pounds of sausage each week by 1930. In 1911 FRITH'S UNION SLAUGHTER HOUSE provided a variety of meats to local and regional markets.
The competition to attract and then keep a meat packer was intense. Both Maquoketa and Waterloo offered $10,000 in cash and a ten-acre lot exempt from taxes for ten years to the Strobel packing company if it moved from Dubuque. The death of Ryan and the 1890 fire which led to the destruction of the Rath slaughtering plant led to a period in which Dubuque's fortunes as a meat packer drifted until the establishment of the CORN BELT PACKING COMPANY in 1919. This company was followed by the re-emergence of the meatpacking giant Dubuque Packing Company and its successor FDL FOODS INC.